Forget Osteoarthritis, This New Breakthrough Promises to End the Pain

Email

A team of researchers at Harvard University just reported a fantastic new medical breakthrough – in the form of a hydrogel.

The compound is made mostly of water, but it's almost unbelievably tough, strong, and resilient. It can stretch to more than 20 times its original length.

Not only that, but it can actually heal itself, too. Given time to relax between stretches, the bonds in the compound are able to "re-zip," self-repairing any cuts or breaks.

Think about the major impact this could have on medicine.

As some experts quickly pointed out, the new gel could be used to engineer human tissue. No doubt, that would be huge. We could someday use a version for skin grafts for burn victims, or to grow tissue for other needs, like organ transplants.

But I'm more excited about a much more immediate use for the hydrogel – one that could benefit the nearly 30 million Americans who suffer from osteoarthritis.

This is a painful condition in which cartilage wears out around the joints such as the knees and elbows. The risk of osteoarthritis onset grows with age, particularly for people over the age of 45.

That's why so many seniors have bad knees, elbows, or shoulders that are stiff and seem to hurt all time. Many take pain relievers every day, but even the strongest over-the-counter drugs can't get rid of all the pain all the time.

And it's not just seniors who hurt – torn cartilage is a leading form of sports injury across all age groups.

Right now there is no cure. Finding one could save the country a small fortune. Experts estimate that osteoarthritis costs us more than $186 billion a year in medical care, drugs, and lost wages.

We're talking about nearly $2 trillion a decade – and that's just here in the U.S.

Not only that, but this is clearly a growth market. The "graying of America" promises to greatly increase the number of these arthritis cases.

As I see it, in the very near future, doctors will be able to go in and actually remove the bad or torn cartilage that's causing you pain. They'll replace it with a hydrogel that is much stronger and more resilient than the original organic substance with which you were born.

In the Era of Radical Change, we will continue to see a steady stream of advances like this – breakthroughs that will help us live longer and healthier lives.

Hey, longevity is good. But quality of life is vital.

What's the point of living to 100 if your knees hurt so bad you can barely walk? Or your shoulder floods with you so much pain you can't pick up your grandkids?

But this new compound promises to change all that. It could even help a century-old man take up long-distance running again…

No doubt there will be plenty of opportunity for smart companies and their investors to become filthy rich in the process.

But just getting rid of a painful condition that afflicts hundreds of millions of people around the world ranks as a major "win" in my book.

Let's take a look at how the team at Harvard did it…

To create this super-gel, the group of researchers combined two different hydrogels, each of which is pretty weak on its own.

The main ingredient is the first gel, polyacrylamide, used in make-up and skin lotions. The team combined eight parts of this with one part of the second gel, alginate. It's a seaweed extract often used to make food thicker.

Now here's the part I think is just plain brilliant…
Once combined, the two polymers form a complex network of cross-linked chains that reinforce each other. That's what gives the gel its incredible strength. The chemical structure of this network allows the molecules to pull apart and expand over a large area, rather than become brittle or simply break. (You can see are several good pictures of how this works in the Harvard press release right here.)
If the gel suffers a tiny crack as it stretches, the chemical bonds will repair themselves. It seems nothing can weaken this substance. Team members showed that even when the gel sustains a major hole, it can still stretch to 17 times its initial length.

Therein lies its promise. For it to work in the body and replace cartilage, the gel must be able to expand and contract millions of times under pressure without breaking.

And since it's made of water and two benign compounds, it's almost certain the gel will work in the body without harmful side effects.

We're still several years from proving this will indeed work in humans to replace worn-out cartilage.

That will require many computer models, then animal testing, and then finally human trials. But I believe that if this gel runs into a dead end, something else will take its place. We just have so many bright minds working on problems like these, I know we will succeed in the long run.

It's only a matter of time before millions find lasting relief from the effects of osteoarthritis and sport injuries.

Related Articles and News:

Join the conversation. Click here to jump to comments…

About the Author

Michael A. Robinson is one of the top financial analysts working today. His book "Overdrawn: The Bailout of American Savings" was a prescient look at the anatomy of the nation's S&L crisis, long before the word "bailout" became part of our daily lexicon. He's a Pulitzer Prize-nominated writer and reporter, lauded by the Columbia Journalism Review for his aggressive style. His 30-year track record as a leading tech analyst has garnered him rave reviews, too. Today he is the editor of the monthly tech investing newsletter Nova-X Report as well as Radical Technology Profits, where he covers truly radical technologies – ones that have the power to sweep across the globe and change the very fabric of our lives – and profit opportunities they give rise to. He also explores "what's next" in the tech investing world at Strategic Tech Investor.

Read full bio

  1. Greg Hill | September 12, 2012

    Great news

  2. MASH18858 | September 13, 2012

    where can i review other peoples replys? fhanks

  3. lisacpa@comcast.net | October 26, 2012

    I did pretty well with Molycorp, and sold it all except for 10 shares. When the price seemed to bottom out around $10.40, I bought back in and have made some more money. I keep a close eye on it, though!

  4. michael bortz | December 6, 2012

    what is it what does it cost?

Leave a Reply

Your email address will not be published. Required fields are marked *


seven + 5 =

Some HTML is OK