These 3 Penny Stocks to Watch Have Gained as Much as 487% in 2017

Investors like penny stocks for one simple reason: They offer the potential of triple-digit gains or even quadruple-digit gains. Today, we're going to show you the top penny stocks to watch before 2018, including three of the year's biggest gainers.

After the list, we'll also show you another company that's one of Money Morning Small-Cap Specialist Sid Riggs's favorite small-cap stocks to buy for 2018.

First, here are three of 2017's biggest penny stock gainers, one of which is up 487% this year…

Penny Stocks to Watch No. 3: AVEO Pharmaceuticals Inc.

AVEO Pharmaceuticals Inc. (Nasdaq: AVEO) is a Cambridge-based pharmaceutical company that specializes in treatments for cancer and other related diseases.

AVEO stock has skyrocketed 487% to $3.17 so far in 2017, with 441% of that rally taking place since June 23. This was when the company received its latest drug approval in Europe.

The approved drug is Tivozanib, which treats patients with advanced renal cell carcinoma. This is the most common type of kidney cancer, and it's also anticipated to be one of the fastest-growing cancers over the next decade.

Back in 2013, AVEO failed to get FDA approval for Tivozanib in the United States, but the firm does have an ongoing phase 3 trial expected to wrap up in Q3 2018. The approval of the drug in Europe will help add to the company's bottom line in 2018, which is why we'll keep watching AVEO stock next year.

Penny Stocks to Watch No. 2: Pieris Pharmaceuticals Inc.

Pieris Pharmaceuticals Inc. (Nasdaq: PIRS) is a Boston-based biotech that develops treatments for asthma and anemia.

The PIRS stock price is up 255.8% to $5.01 so far this year, with 170.8% of those gains happening since May 3. That was when Pieris announced a collaboration agreement with AstraZeneca Plc. (NYSE ADR: AZN).

Under the terms of the partnership, Pieris is going to work on an asthma drug called PRS-060, which is supposed to start phase 1 trials this year. Once this happens, Pieris will receive $12.5 million from AstraZeneca, in addition to the $45 million already paid upfront.

In addition to PR-060, Pieris announced on Oct. 2 that it began dosing patients in their phase 1 clinical trial of PRS-343. This is meant to treat tumors commonly caused by breast, ovarian, and pancreatic cancers.

Penny Stocks to Watch No. 1: Verastem Inc.

Verastem Inc. (Nasdaq: VSTM) is a cancer-focused biotech firm based in Needham, Mass. It's engaged in clinical trials for a variety of drugs that treat lung, ovarian, and pancreatic cancers, among others.

Shares of VSTM stock are up 251.8% to $3.91 in 2017. The stock rallied 28.1% on Sept. 6 alone after the firm announced it would expand trials of its leukemia treatment Duvelisib to patients suffering from peripheral T-cell lymphoma (PTCL). The FDA has given Duvelisib fast-track status for the treatment of PTCL, which strongly indicates the drug will be available to the public in 2018.

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Verastem is also producing a drug called Defactinib, which is made to disrupt the focal adhesion kinase pathway crucial to cancer cell survival and strength. This particular drug could potentially treat pancreatic and ovarian cancers as well as mesothelioma. This drug is at the end of phase 1 trials and is currently entering phase 2.

The gains from these three penny stocks are impressive, which is why investors should add them to their watch list.

But we don't recommend investing in any of them. They've already seen triple-digit gains this year, and our Money Morning experts focus on finding stocks with gains in front of them.

Today, Money Morning Small-Cap Specialist Sid Riggs is giving you one of the best small-cap stocks to invest in for 2018.

This firm operates in the mobile banking transactions market, which is set to grow 716% over the next four years. According to Sid's research, this growth will boost total revenue for the tech firms that make these transactions possible to $865 billion in 2021.

Here's today's pick…

The Best Small-Cap Stock to Buy in the Mobile Banking Market