Penny stocks10 Top Penny Stocks to Watch This Week - and One You Need in Your Portfolio October 22, 2018 by Money Morning Staff Reports Eight of our top penny stocks to watch generated triple-digit returns last week, demonstrating the immense profit potential of penny stocks. Our top penny stock, vTv Therapeutics Inc., generated a 356% gain. Investors are increasingly bullish on the commercial therapy firm thanks to reports that vTv will present revolutionary results on a treatment for Alzheimer's disease later this month.