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Blackbaud Inc. (Nasdaq: BLKB) This Charleston, S.C.-based company has an unusual niche for a publicly traded software firm. The company caters to nonprofits such as research foundations and universities. The company has 29,000 clients that use its software to manage fundraising, accounting, online marketing, and payment services. With a market cap of $1.6 billion, Blackbaud has operating margins of 11% and a 20% return on equity. It recently grew its quarterly earnings by some 43%.